The 5 Components of a PICOT Question

It is important to understand the components of a PICOT question to come up with an appropriate PICOT question formula.

PICOT is a mnemonic, meaning that it bears five main components.

  1. Population (P) – Who is the specific population? Where is the population? What is the clinical problem, issue, or health condition related to clinical care the population is facing?
  2. Intervention (I) – What is the evidence-based nursing practice intervention, treatment, or care management strategy?
  3. Comparison (C) – Who is the comparison population that will not receive the intervention?
  4. Outcome (O) – What are the anticipated consequences or clinical outcomes for the population that received the intervention?
  5. Time (T) – What length of time is the nursing intervention being performed for the patient/population to achieve the outcome?

For example, consider a question: Does handwashing among healthcare workers reduce hospital-acquired infections and associated risks compared to non-compliance to hand hygiene protocols?

The question above has the PICO elements. Let’s explore it further:

(problem, patient, or population) – Healthcare workers

(Intervention/Exposure) – handwashing

(Comparison) – non-compliance with hand hygiene

(outcome of interest) – reduced hospital-acquired infections and associated risks

Given the 5 components, which you can list on your PICOT question template, you can then convert the components into a PICOT formula in the format below:

In _________ (P), how does _________ (I) compared to _________(C) affect _______(O) within _______ (T)?

In _______(P), what is the effect of _______(I) on ______(O) compared with _______(C) within ________ (T)?

The scope of the formula will depend on the type of pattern you choose, as we shall explore in the next section.